Depending on the management tool you are using, you may need to specifically enable or configure Microsoft Defender Antivirus protection.
See the table in Deploy, manage, and report on Microsoft Defender Antivirus for instructions on how to enable protection with Microsoft Intune, Microsoft Endpoint Configuration Manager, Group Policy, Active Directory, Microsoft Azure, PowerShell cmdlets, and Windows Management Instruction (WMI).
Some scenarios require more guidance on how to successfully deploy or configure Microsoft Defender Antivirus protection, such as Virtual Desktop Infrastructure (VDI) environments.
The remaining article in this section provides end-to-end advice and best practices for setting up Microsoft Defender Antivirus on virtual machines (VMs) in a VDI or Remote Desktop Services (RDS) environment.